Office Phone: 416-946-5602
Office Location: Lash Miller Chemistry Building Room 151
Office Hours and/or Leave Status: by appointment—please send an e-mail
BA (Oxford University)
PhD (Imperial College of Science Technology and Medicine)
Rob Batey is a professor and chair of the Department of Chemistry in the University of Toronto. His teaching and research interests are in the general area of organic chemistry with a focus on organic synthesis and its application to biology and medicine. This program encompasses the development of new organicreactions, the synthesis of depsipeptide, alkaloid and other heterocyclic natural products, and their application as anticancer and antibiotic agents. The use of organoboron reagents, iminium ion chemistry, cycloaddition, electrocyclic and sigmatropic reactions are a hallmark of his research. His work has been recognized by several awards, including most recently the Canadian Society of Chemistry Bader Award(2014) and a Faculty of Arts and Science Outstanding Teaching Award (2012–13).
- “A Lanthanide(III) Triflate-mediatedMacrolactonization / Solid-Phase Synthesis Approach for Depsipeptide Synthesis.” Goodreid,J. D.; da Silveira dos Santos, E.; Batey, R. A. Org.Lett., 2015, 17, 2182-2185. (DOI: 10.1021/acs.orglett.5b00781).
- “Total Synthesis and Bacterial Testing of theAntibiotic A54556 Cyclic Acyldepsipeptides Isolated from Streptomyceshawaiiensis.” Goodreid, J. D.; Wong, K.; Leung, E.; McCaw, S.E.; Gray-Owen, S.; Lough, A.; Houry,W. A.; Batey, R.A.J. Nat.Prod., 2014, 77, 2170–2181. (DOI: 10.1021/np500158q)
- “Organoboron-based Allylation Approach to the TotalSynthesis of the Medium-ring Dilactone (+)-Antimycin A1b.” Janetzko, J.; Batey, R.A. J. Org. Chem., 2014, 79, 943–954. (DOI: 10.1021/jo501134d)
- “An Organotrifluoroborate-based Convergent TotalSynthesis of the Potent Cancer Cell Growth Inhibitory Depsipeptides Kitastatinand Respirantin.” Beveridge, R.E.; Batey, R.A. Org. Lett., 2014, 16, 2322–2325. (DOI: 10.1021/ol500484f)
- “A Short Total Synthesis of the MarineSponge Pyrrole-2-aminoimidazole Alkaloid(±)-Agelastatin A.” Duspara, P.A.; Batey, R.A. Angew. Chem. Int.Ed., 2013, 52, 10862–10866. (DOI: 10.1002/anie.201304759)
For a complete list of publications and further information on his research group,see: http://www.chem.utoronto.ca/staff/RAB/index.html